top of page
Original Research Publications
Recent publications (since 2023)
Nature Communications, 2025. Microglia-specific regulation of lipid metabolism in Alzheimer’s disease revealed by microglial depletion in 5xFAD Mice
Neurotherapeutics, 2025. Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer’s disease
The Journals of Gerontology Series A, 2025. Symposia Report of The Annual Biological Sciences Section Meeting of the Gerontological Society of America 2023, Tampa, Florida
bioRxiv, 2024. Microglia-Dependent and Independent Modulation of Brain Lipid Metabolism in Alzheimer’s Disease Revealed by Pharmacological and Genetic Microglial Depletion
Science Advances, 2024.
Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease
iScience, 2024.
Functional regulation of microglia by vitamin B12 alleviates ischemic stroke-induced neuroinflammation in mice
bioRxiv, 2023. Multi-omics analyses reveal novel effects of PLCγ2 deficiency in the
mouse brain
Nature Medicine, 2023.
Senolytic therapy in mild Alzheimer’s disease: a phase 1 feasibility trial
Clinical and Translational Medicine, 2023.
Central nervous system sulfatide deficiency as a causal
factor for bladder disorder in Alzheimer’s disease
Glia. 2023.
Adult-onset depletion of sulfatide leads to axonal degeneration with relative myelin sparing
Biomedicines. 2023.
Compromised Myelin and Axonal Molecular Organization Following Adult-Onset Sulfatide Depletion
Neural Regeneration Research, 2023.
Myelin lipid deficiency: a new key driver of Alzheimer's disease
bottom of page