Palavicini Lab Grants
The Palavicini lab in collaboration with multiple laboratories at UT Health SA and external institutions, frequently submits grant applications to the National Institutes of Health and foundations. Below you can find a list of our most recently funded grants.
Active
Alzheimer’s Association Research Grant For All (AARGA)
Gene-Environment Synergy: Circadian and Metabolic Triggers in MAPT-GR Mice
Palavicini JP (PI)
Koronowski K (Co-I)
04/01/2026-03/31/2029
The goals of this project are to elucidate the mechanisms by which circadian disruption and metabolic stress interact with genetic risk to influence tauopathy; and reveal the ability of time-restricted feeding to ameliorate AD pathology in a humanized mouse model.
Total Award Amount (including Indirect Costs): $200,000.00
UT Rising STAR Award
Palavicini JP (PI)
09/01/2025-08/30/2026
The STARs (Science and Technology Acquisition and Retention) program provides funding to help purchase state-of-the-art research equipment and make necessary laboratory renovations to encourage faculty members to perform their research at a UT institution.
Total Award Amount (including Indirect Costs): $150,000.00
San Antonio Claude D. Pepper Older Americans Independence Center (NIH/NIA P30 AG044271)
Preclinical Research Resource Core Associate Leader
Volpi E (PI)
Palavicini JP (co-I)
09/01/2025-08/31/2030
The Pre-clinical Research Core (RC1) of the San Antonio Pepper Older Americans Independence Center provides the knowledge, skills, and technical support to assist investigators in using the common marmoset (Callithrix jacchus) as a pre-clinical model for translational geroscience research.
Aging Animal and Functional Assessment Core Associate Leader
Salmon A; Strong R (MPI)
Palavicini JP (co-I)
06/17/2025-05/31/2030
The Animal Core provides leadership, innovation, facilities and an expertly trained staff to enable investigators to provide foundational resources for studies in mammalian aging centered on gerotherapeutic application and delineation of biology of aging mechanisms.
2024 William and Ella Owens Medical Research Foundation Award
Modeling late-onset Alzheimer’s via gene-environment interactions: Effects of circadian disruption in mice expressing the whole human MAPT gene
Palavicini JP (PI)
Koronowski K (co-I)
05/01/2024-04/30/2026
The goals of this project are to model LOAD in mice using novel and clinically-relevant combinations of gene-environment interactions and assess the sex-specific effects of circadian asynchrony on AD neuropathologies and cognitive performance.
Total Award Amount (including Indirect Costs): $200,000.00
Pepper OAIC Multi-Center Pilot grant
Inhibition of ceramide synthesis: a viable strategy to reverse metabolic determinants of sarcopenic obesity?
Palavicini JP (PI)
Murton AJ (co-I)
10/01/2023-05/30/2026
The goals of this project are to establish marmosets as a model of sarcopenic obesity and test the hypothesis that ceramide lowering will improve metabolic abnormalities.
Total Award Amount (including Indirect Costs): $100,000.00
Completed
Glenn Foundation for Medical Research
and AFAR Grant for Junior Faculty
Mechanisms and consequences of ceramide losses in long-lived growth hormone deficient mice
Palavicini JP (PI)
07/01/2022-06/30/2024
The goal of this study is to test the hypothesis that systemic ceramide reductions are sufficient and necessary for improved healthspan in growth hormone deficient mice.
Total Award Amount (including Indirect Costs): $125,000.00
Alzheimer’s Association AARG-D 846013
PLCG2 AD variants in microglial lipid metabolism and calcium signaling
Hopp S/Palavicini JP (MPI)
10/01/2021-09/30/2024
The goal of this project is to determine the effects of PLCG2 risk and protective variants on brain and microglia lipid metabolism and downstream signaling.
Total Award Amount (including Indirect Costs): $150,000.00
Cure Alzheimer’s Fund
Han X/Palavicini JP (MPI)
01/01/2023-12/31/2023
Total Award Amount (including Indirect Costs): $200,000.00
NIH/NIA P30 AG044271 (7973)
PI: Shireman P (REC)/RL5 Scholar: Palavicini JP
12/01/2021-11/31/2023
Total Award Amount (including Indirect Costs): $200,000.00
ADA Grant #1-15-MI-07
Mechanistic study on sulfatide deficiency in diabetes and its relationship with dementia.
Han X (PI)/Palavicini JP (Fellow)
01/01/15 –12/31/17
American Diabetes Association
Role: Postdoctoral Research Fellow.
Total Award Amount (including Indirect Costs): $121,500.00
